Heartburn: Why your antacids aren’t working: Harvard doc reveals |


Taking antacids but still have heartburn? Harvard doctor reveals two hidden culprits

Struggling with heartburn despite taking antacids regularly? Well, then it’s time to look a little deeper. Persistent acid reflux, even after gulping all those antacids, is a red flag worth investigating. Dr Saurabh Sethi, a leading California-based gastroenterologist trained at Harvard and Stanford, has explained the hidden culprits behind this condition. “In clinic, I often see patients who are treating symptoms daily, but we haven’t fully explored the underlying driver,” Dr Sethi said in a recent newsletter. What are these two missed contributors? Let’s take a look.

Lactose intolerance

Most people are lactose intolerant, and it’s one of the key contributors to heartburn. “Nearly two-thirds of the global population has some degree of lactose malabsorption. When lactose isn’t digested properly, it can cause bloating and gas. That increased abdominal pressure can worsen reflux symptoms in susceptible individuals,” Dr Sethi explained.

H. pylori infection

Another hidden contributor is the stomach bacterium known as H. pylori. “This stomach bacterium affects a significant portion of the world’s population. It can cause gastric inflammation and, in some cases, alter acid dynamics, which may contribute to upper GI symptoms, including reflux-like discomfort,” he added.Dr Sethi also stressed that these two culprits are not necessarily the cause behind every reflux case. “But in patients with persistent symptoms, they’re worth evaluating.”

Dr Sethi’s clinical recommendation

  • If lactose intolerance is suspected, Dr Sethi recommends a trial of lactose-free or plant-based alternatives and monitoring symptom response.
  • If H. pylori is suspected, the gastroenterologist suggests non-invasive testing (breath or stool test), followed by appropriate treatment if the result is positive.

The doctor also added that, in some selected cases, further evaluation such as endoscopy (EGD) may be required, especially if there are alarm symptoms or a poor response to therapy.“I’ve had patients treated for H. pylori whose long-standing symptoms improved significantly. The key is identifying the right cause,” he stressed.According to Dr Sethi, if your heartburn isn’t improving even after taking antacids, you should consult your physician about whether further evaluation makes sense. “Treat the root cause, not just the symptom,” he reminded.So, if you are struggling with acid reflux despite taking antacids for long periods, it’s time to book an appointment. It is not a minor inconvenience. It could be a warning sign your body is waving, and you certainly don’t want to ignore it.Disclaimer: The information in this article is for educational purposes only and should not be considered medical advice. Always consult a qualified healthcare professional before making any changes to your diet or health routine.



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